MAPK

Abstract This research provides a comprehensive analysis of mitogen-activated protein kinase (MAPK) signaling pathways, which play crucial roles in cellular processes including proliferation, differentiation, apoptosis, and stress responses. Introduction MAPK pathways are evolutionarily conserved signaling cascades that regulate fundamental cellular processes. Understanding these pathways is essential for comprehending normal cell function and disease mechanisms, particularly in cancer and inflammatory diseases. MAPK Pathway Overview Major MAPK Pathways ERK1/2 Pathway: Involved in cell proliferation and differentiation JNK Pathway: Stress response and apoptosis p38 MAPK Pathway: Inflammation and cell cycle regulation ERK5 Pathway: Cell survival and proliferation Research Focus Signal Transduction Mechanisms Detailed analysis of how MAPK pathways transmit signals from cell surface receptors to nuclear transcription factors. ...