P53 and CENPA Clustering in MCF10A Cells Using K-means Algorithm
Abstract This research applies advanced bioinformatics and machine learning techniques to analyze the clustering and regulation of P53 and CENPA genes in MCF10A cells. Using gene expression profiles and the K-means clustering algorithm, we identify patterns of gene regulation and co-expression networks. Introduction P53 - The Guardian of the Genome The P53 tumor suppressor gene plays a critical role in: Cell cycle regulation DNA repair Apoptosis Genomic stability CENPA - Centromere Function CENPA (Centromere Protein A) is essential for: ...